Machine Learning Meetings and Events

Group Meetings: Group meetings are held Mondays from 11am to Noon (talk starts 11:10am) in D.L. Pratt 290C unless otherwise noted. Meetings are coordinated by Hugo Larochelle.

Tea Talks: Tea talks are held every Wednesday at 4:00pm in D.L. Pratt 290C. Talks should be simple, accessible, and not exceed 15 minutes. Speakers bring snacks, make tea, and provide a copy of the presented paper.

Group Meeting Jan 12, 2009: Dimensionality and Dynamics in the Behavior of C. elegans

Speaker: William Ryu
Abstract:
A major challenge in analyzing animal behavior is to discover some underlying simplicity in complex motor actions. We have developed a video-tracking microscope to follow the locomotary behavior of C. elegans as it freely crawls on the surface of an agar plate, and quantify this behavior using machine vision processing. Here, we show that the space of shapes adopted by the nematode Caenorhabditis elegans is low dimensional, with just four dimensions accounting for 95% of the shape variance. These dimensions provide a quantitative description of worm behavior, and we partially reconstruct “equations of motion” for the dynamics in this space. These dynamics have multiple attractors, and we find that the worm visits these in a rapid and almost completely deterministic response to weak thermal stimuli. Stimulus-dependent correlations among the different modes suggest that one can generate more reliable behaviors by synchronizing stimuli to the state of the worm in shape space. We confirm this prediction, effectively “steering” the worm in real time.